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The U.S. Food and Drug Administration has approved Contrave (naltrexone hydrochloride and bupropion hydrochloride extended-release tablets) as treatment selection for chronic weight reduction in addition to a reduced-calorie diet and physical exercise. Using two separate drugs to lose weight can be very effective you can find combinations before the FDA now awaiting approval. When dealing with weight reduction and the people that go through it you ought to err assisting caution and permit the FDA do its job and demand some study be done so that the public understands the side effects and perils associated with the medications before we bring them. Keep in mind that drug companies are in business to generate money and that they would say everything to keep people on his or her medications. Researchers discovered that participants investing in this drug for a year, dropped a few pounds within four weeks and have kept the weight off through the entire 56 weeks in the study. Contrave can be a combination from the drugs naltrexone and bupropion, which appears to reflect a whole new trend of weight-loss drugs that are made up of several active ingredient, which might make them far better and safer. Combo-pilling will be the newest fad or better yet the newest ahead under scrutiny and thus it is just more publicly known recently, comb-pilling for weight reduction has been around since the eighties. The biggest reason that using a combination of pills is starting to become popular may be the fact that at the time of right now there aren't long term prescription weightloss pills that have been authorized by the FDA besides orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications even though some of the combinations have been rejected or have yet to be approved by the FDA. Seizures really are a side effect with Contrave and mustn't be taken in those with seizure disorders. The drug could also raise blood pressure level and heart rate, and mustn't be used in individuals with a history of cardiac arrest or stroke in the earlier six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy with the drug. The FDA also warned that Contrave can raise hypertension and pulse rate and must not be used in patients with uncontrolled high blood pressure, and also by a person with heart-related and cerebrovascular (circulation system dysfunction impacting mental performance) disease. Patients having a history of heart attack or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes having a boxed warning to alert medical professionals and patients to the increased likelihood of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for stopping smoking. Approving a drug using this many potentially lethal unwanted effects is inconsistent with the mission statement of the FDA. The power from the drug manufacturing lobby is blatantly evident inside the approval of many drugs requiring 'post-marketing' studies which might be clearly significant to overall drug safety inside US.